Changes in personality after heart transplantation are attracting attention. After the transplant began。 In some cases, those who hated classical music have developed their passion for this genre after receiving the hearts of musicians. The recipient died later I hold the violin case。
In another case, a 45 -year -old man The heart of a 17 -year -old boyHe loves to wear headphones and listen to loud music.
Recent research Suggests that Heart transplant recipients may not be unique to experience changes in personality. These changes may occur after transplanting any organs.
May I explain this? One proposal is that this is the placebo effect. New leasing of life Give people More clear temperament。 Other transplant recipients are suffering The guilt of depression and seizures others Psychological problem It may be seen as a change in personality.
However, there are several evidence that suggest that all of these changes in personality are not psychological. Biology may also play a role.
The transplanted organs cells execute the expected functions -heart cells are beaten, kidney cells are filtered, and liver cells are metabolized, but also plays a role elsewhere in the body. Many organs and their cells are released hormone or Signal transmission molecules It is effective in the body and elsewhere in the body.
The heart seems to be most commonly related to changes in personality. Chamber contains peptide hormone “Atrial sodium urgent peptide” and “Brain sodium urine peptide”Affects the kidneys, can help regulate the balance of body fluids in the body.
VesnaArt/ShutterStock
They will also play Role in electrolyte balance and Hindrance The activities of our nervous system are Response to battle or flight。 There is a cell in charge of this Hypothalamus -Part of the brain that plays a role in everything, from constant (biological balance) to mood.
Thus, donor organs, which have a potential base -level hormone and peptide production different from the original organs, may change the mood and personality of the recipient through the release of the substance.
It is shown that there is a sodium urine peptide level Higher than after transplantation -A, don't go back normally. Some of the altitude is probably a reaction to surgical trauma, but not all.
Memory stored outside the brain
Bodystore Brain memory。 We can access them when we are thinking or be caused by sight and smell. but Memories are basically neurological processes The nerves convey the urge to each other and exchange special chemicals (neurotransmitters) at the interface between them.
During the transplant surgery, many of the nerves that control the function of the organs are cut and cannot be touched, but this does not mean that the nerves in the organs are still not functioning. In fact, there is evidence that they may be so Partially restored One year after surgery.
These neurological actions and interactions feed on the nervous system of the recipe, establish a physiological reaction, and affect the recipient's personality according to the memories of donors.
It is known that cells from donors are circulating Reciper's body And donor DNA is found in the body of the recipe Two years after transplantation。 This also raises the question of where the DNA is going and what actions take.
One of the things we do Stimulate the immune response。 These immune response may be sufficient to cause a personality change because it is known that long -term and low -level inflammation can be made. Change personality characteristicsExtroistics and conscience.
If the combination of mechanism or mechanism is responsible, this research field requires further investigations, so that the recipient can understand physical and psychological changes that may occur after surgery. I'll do it.
