Non credo ai miracoli ne ho visti troppi (I don't believe in miracles. I've seen too many miracles).
Oscar Wilde, Irish poet and playwright. (1854-1900) Figure 1.
Figure 1: Oscar Wilde.
Public domain. Elliott and Fry 1881.
As an Irishman, the idea of drinking Guinness without alcohol seems anathema. However, it can and does succeed. This is called Guinness 0.0 and I tasted it as shown in Figure 2 and it was fine. A few years ago, the Guinness Company tried to sell Guinness with reduced alcohol content. The central message was: “They said it would never be possible.” They were right, “Guinness Light” was a huge failure. Louise Eccles writes for the Sunday Times [1] praises the benefits of Guinness 0.0 and the alcohol extraction procedure. This is a fairly expensive process, which also explains why Guinness costs 0.0 even in countries that do not impose high government taxes on non-alcoholic beverages. [2].
Figure 2: Glass of Guinness 0.0.
Photo by Brenda Moore-McCann.
I don't think Diageo (owner of Guinness) sells wine, at least in Ireland. I remember back in the days before political correctness (PC), Guinness was served to breastfeeding mothers in Irish maternity hospitals. The ruse was that Guinness contained a lot of iron. Probably so! At the time, my wife was in the hospital giving birth to our first child. She didn't like Guinness. I visited her every day and happily ate her ration. Unfortunately, the PCs are now in control and I am no longer the father of my child. The custom of offering Guinness to nursing mothers has become a distant memory.
Guinness 0.0 aside, who would have thought that English sparkling wine could rival Champagne? I've mentioned this several times, but [3] But Lize Enfield writes for the BBC [4] pointed out in September 2024 that the efforts of many wine farmers have finally paid off, partly due to the effects of climate change. English sparkling wine is so good that many major champagne houses have purchased land in the UK to develop vineyards, most notably Pommery Wines, Tettinger Wines and the California-based Jackson family. Examples include wine. She points out: The Romans were the first to bring vines to Britain 2000 years ago. A thousand years later, the Normans also succeeded in establishing viticulture, but viticulture declined in the Middle Ages. Despite the wave of interest sparked by 18th century adventurers, it wasn't until the 1970s that Britain's winemaking renaissance really began..
Has there been a change in hematology? Yes. Of the first 200 patients who received allogeneic bone marrow transplants, there were no long-term survivors. Thanks to the tenacity of E Donal Thomas and his colleagues and the discovery of the HL-A system, along with improved supportive care, the situation is now much more satisfactory.
Atsuta and colleagues in the Haematologica article [5] They point out that the use of HCT has doubled around the world in about a decade, at varying rates and with important changes in donor matching, a sign that access to HCT has improved around the world. Masu. Although narrowing, there remains a large gap between developing and non-developing countries. Unfortunately, but not surprisingly, access to HCT is higher in countries with higher gross national income per capita (GNI).
The latest EBMT newsletter reports that over 10,000 CAR-T injections have been reported to the registry. CAR T-cell therapy and other cellular immunotherapies are advanced therapeutic medicinal products (ATMPs) manufactured from living primary human cells sourced from hospitals or blood banks. CAR T-cell therapy is a highly individualized medicine that is administered to patients in a single treatment, as opposed to other immunotherapies such as bispecific antibodies that are administered sequentially over an extended period of time. . Long-term follow-up is required to prove the safety of the treatment and durability of efficacy [6].
Immunotherapy is usually performed as an adjunct to chemotherapy and plays a decisive role in the treatment of hematological malignancies. Immunotherapy not only increases the effectiveness of some chemotherapy regimens but also helps reduce acute toxicity. Over time, the exact role of immunotherapy in the treatment of hematological malignancies will undoubtedly be precisely defined and its use will increase.
I'm not a surgeon, but in the field of keyhole surgery and robotic surgery, we've seen much less toxicity and much shorter hospital stays than traditional methods. This is especially true for methods that traditionally required opening the omentum.
Changes are occurring in the worlds of wine and medicine. I hope you can benefit from the wine change without taking advantage of the drug change.
This will be my last edit, so I wish you all the best. I really enjoyed writing it, so I hope you enjoy reading it. I wish you all the best.
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